Normal Fusion for 3D Integrated Visualization of SPECT and MR Brain Images

Multimodality visualization aims at efficiently presenting integrated information obtained from different modalities, usually combining a functional modality (SPECT, PET, fMRI) with an anatomical modality (CT, MRI). This chapter presents a technique for 3D integrated visualization of SPECT and MR brain images, where MRI is used as a framework of reference for the display of the SPECT data. Methods: A novel technique for 3D integrated visualization of functional and anatomical information, called Normal Fusion, is presented. With this technique local functional information is projected onto an anatomic structure. Results: The Normal Fusion technique is applied to three cases of SPECT/MRI integration. The results are presented, discussed and evaluated for clinical relevance. Conclusions: The results for 3D integrated display of SPECT and MR brain images indicate that the Normal Fusion technique provides a potentially comprehensive and diagnostically valuable presentation of cerebral blood perfusion in relation to the anatomy of the brain. 42 Normal Fusion for 3D Integrated Visualization of SPECT and MR Brain Images